Title: Radiation therapy for benign central nervous system disease.

Authors: Tsao MN; Wara WM; Larson DA
Address: Department of Radiation Oncology, University of California San Francisco, San Francisco, California 94143, USA.

Source: Semin Radiat Oncol, 9(2):120-33 1999 Apr


The most common indication for the use of radiation therapy in the treatment of benign central nervous system disease is for the treatment of benign brain tumors, such as meningioma, pituitary adenoma, acoustic neuroma, arteriovenous malformation, and craniopharyngioma.

Other less common benign intracranial tumors treated with radiation include chordoma, pilocytic astrocytoma, pineocytoma, choroid-plexus papilloma, hemangioblastoma, and temporal bone chemodectomas.

Benign conditions, such as histiocytosis X, trigeminal neuralgia, and epilepsy, are also amenable to radiation treatment. There have also been reports of radiosurgery being used for the treatment of movement disorders and psychiatric disturbances, such as obsessive-compulsive and anxiety disorders.

For benign brain tumors, radiation therapy as either primary or adjuvant therapy plays an integral role in improving local control.

In the treatment of trigeminal neuralgia, epilepsy, tremor, and some psychiatric disturbances, radiosurgery may help ameliorate or eliminate some symptoms.

Patients with benign central nervous system disease are expected to live a long time.
(Inez's note: And would like to be able to hear during this time.)

As such, treatment should be highly conformal and based on three-dimensional planning using magnetic resonance imaging, computed tomography, or both.

It is critical that damage to normal brain be minimized.

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